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EvolutionaryScale ESM-3

Frontier protein language model for biological design.

Domain ModelSpecialized LLMDomainSpecificFoundation

About

Frontier protein language model for biological design. EvolutionaryScale, founded by former Meta FAIR researchers behind the original ESM (Evolutionary Scale Modeling) protein language models, ships ESM-3 — a frontier-class foundation model for protein sequences with applications spanning drug discovery, enzyme design, and synthetic biology. ESM-3 is one of the clearest examples of a domain foundation model that meaningfully extends what general LLMs cover, because protein language is genuinely outside natural-language training distribution.

Enterprise Readiness

from cataloged data

9/100 · Emerging

Security & ComplianceNot disclosed

No compliance certifications listed

Deployment FlexibilityPartial

Cloud-based: Cloud

Integration DepthNot disclosed

No integrations listed

Proven AdoptionNot disclosed

No published adoption signals

Company MaturityNot disclosed

Company maturity not disclosed

Composite of public compliance, deployment, integration, adoption, and company signals. “Not disclosed” reflects gaps in available data, not a vendor deficiency.

Independently sourced

Pulled directly from regulator filings and platform APIs. No vendor or editorial input.

Activity classifier

Active

last GitHub commit 0d ago

GitHub API2026-05-27

evolutionaryscale

SDK / client libraries· active 2mo ago

Python · HCL

Pricing snapshot2026-05-27

No pricing page found

Enterprise Use Cases

Integrations

How EvolutionaryScale ESM-3 compares

Tool	Readiness	Pricing	Deployment	Compliance	Integrations
EvolutionaryScale ESM-3	9 · Emerging	Paid	Cloud	—	0
OpenAI Enterprise	76 · Strong	Enterprise	Cloud	SOC 2, GDPR, HIPAA	5
Anthropic Claude	70 · Strong	Paid	Cloud	SOC 2, GDPR	5
DeepSeek	62 · Established	Freemium	Cloud, Self-Hosted, On-Premise	SOC 2	5

Peers from the same category, ranked by Enterprise Readiness. Readiness is a composite of cataloged compliance, deployment, integration, adoption, and company signals.

Frequently Asked Questions

What is EvolutionaryScale ESM-3 used for?

EvolutionaryScale ESM-3 is frontier protein language model for biological design.

Is EvolutionaryScale ESM-3 free, and how is it priced?

EvolutionaryScale ESM-3 is a paid product. Pricing is set by the vendor — check the official site for current plans.

How can EvolutionaryScale ESM-3 be deployed?

EvolutionaryScale ESM-3 supports Cloud deployment. It is delivered as a cloud-hosted service.

Is EvolutionaryScale ESM-3 enterprise-ready?

Based on cataloged data, EvolutionaryScale ESM-3 has an Enterprise Readiness score of 9/100 (Emerging tier), derived from its compliance, deployment, integration, adoption, and company-maturity signals.

Quick Facts

PricingPaid

DeploymentCloud

CategoryNLP & Language

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